UPDATE
I fixed it! Iḿ not quite sure what I did, but it worked. I tried to execute the commands from the output manually and followed it to the error source: /usr/lib/python3/dist-packages/OpenSSL/crypto.py
I tried some stuff from stackoverflow, but in the end I executed:
sudo apt remove python3-pip
wget https://bootstrap.pypa.io/get-pip.py
sudo python3 get-pip.py
-After reboot-
pip install pyopenssl –upgrade
it showed a missing installation of PyYAML5.1
after running pip install PyYAML==5.1
I reran pip install pyopenssl –upgrade
Finally I retried the Zephyr Setup and it worked!! Perhaps this will assist someone in the future, perhaps not.